Translational research of adult stem cell therapy
نویسندگان
چکیده
منابع مشابه
Translational applications of adult stem cell-derived organoids.
Adult stem cells from a variety of organs can be expanded long-term in vitro as three-dimensional organotypic structures termed organoids. These adult stem cell-derived organoids retain their organ identity and remain genetically stable over long periods of time. The ability to grow organoids from patient-derived healthy and diseased tissue allows for the study of organ development, tissue home...
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PURPOSE OF REVIEW Acute cerebral infarction causes irreversible locally restricted loss of the neuronal circuitry and supporting glial cells with consecutive functional deficits and disabilities. The currently available and effective therapy targets fast vessel recanalization accompanied by symptomatic measures. Research activities focusing on stem cells, which represent a promising source for ...
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Currently, a growing number of small clinical trials are testing the impact of cell-based therapies for heart disease. In order to guide future approaches, it is important in the context of these trials to consider issues pertaining to mechanism of action. To date, the bone marrow has been the most widely studied source of cell-based therapy for heart disease, and this has been followed by skel...
متن کاملAdult stem cell therapy in perspective.
Brave New World Ventricular remodeling and ultimately heart failure are the inexorable consequences of substantial myocardial infarction. In recent years, the understanding that regenerative processes exist at the level of the myocardium has placed stem cell research at center stage in cardiology. Through cellular therapies, the concept of “growing” heart muscle and vascular tissue and manipula...
متن کاملBringing prosocial values to translational, disease-specific stem cell research
BACKGROUND Disease-specific stem cell therapies, created from induced pluripotent stem cell lines containing the genetic defects responsible for a particular disease, have the potential to revolutionize the treatment of refractory chronic diseases. Given their capacity to differentiate into any human cell type, these cell lines might be reprogrammed to correct a disease-causing genetic defect i...
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ژورنال
عنوان ژورنال: World Journal of Cardiology
سال: 2015
ISSN: 1949-8462
DOI: 10.4330/wjc.v7.i11.707